# OnCo record node-positive-penile-cancer (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/node-positive-penile-cancer/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "node-positive-penile-cancer" ;
  schema:name "Node-positive and metastatic penile cancer"@en ;
  schema:alternateName "Advanced penile squamous cell carcinoma"@en, "Inguinal node-positive penile cancer"@en, "Locally advanced penile cancer"@en, "Metastatic penile cancer"@en ;
  schema:description "Node-positive penile cancer is squamous cell cancer of the penis that has reached the lymph nodes of the groin or pelvis, and it is where penile cancer becomes life-threatening. Treatment combines removal of the groin nodes with chemotherapy or chemoradiotherapy before or after surgery, the InPACT trial is testing the best order, and PD-1 antibodies are being added for advanced disease."@en ;
  schema:url <https://onco.cc/cancers/node-positive-penile-cancer/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Penile_cancer> ;
  schema:citation <https://doi.org/10.1200/JCO.2010.29.5477>, <https://www.isrctn.com/ISRCTN36516280>, <https://en.wikipedia.org/wiki/Penile_cancer> ;
  onco:tag "subtype-page", "genitourinary" ;
  onco:related <https://onco.cc/cancers/localised-penile-cancer/>, <https://onco.cc/cancers/penile/>, <https://onco.cc/cancers/metastatic-anal-cancer/> ;
  onco:technologies <https://onco.cc/technologies/sentinel-node/>, <https://onco.cc/technologies/robotic-surgery/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/imrt-igrt/> ;
  onco:targets <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/cemiplimab/> ;
  onco:terms <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/terms/hpv-p16/>, <https://onco.cc/terms/hpv-status/> ;
  onco:trials <https://onco.cc/trials/nct03260023/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pagliaro-neoadjuvant-tip-penile-cancer-jco-2010/>, <https://onco.cc/key-papers/paper-eau-asco-penile-cancer-guideline-eur-urol-2023/> ;
  onco:pipeline <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/cemiplimab/>, <https://onco.cc/trials/nct03260023/> ;
  onco:standardOfCare <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/technologies/sentinel-node/>, <https://onco.cc/technologies/robotic-surgery/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/cemiplimab/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/trials/nct03260023/> .