# OnCo record nogapendekin-alfa (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/nogapendekin-alfa/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "nogapendekin-alfa" ;
  schema:name "Nogapendekin alfa inbakicept"@en ;
  schema:alternateName "ALT-803"@en, "NAI"@en, "nogapendekin-alfa-inbakicept"@en, "Anktiva" ;
  schema:description "Nogapendekin alfa inbakicept is an engineered version of the immune-boosting protein IL-15, given with BCG into the bladder, approved in 2024 for early bladder cancer that BCG alone no longer controls."@en ;
  schema:url <https://onco.cc/drugs/nogapendekin-alfa/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Nogapendekin_alfa_inbakicept> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Nogapendekin%20alfa%20inbakicept>, <https://doi.org/10.1056/EVIDoa2200167> ;
  onco:status "approved" ;
  onco:modality "IL-15 superagonist (intravesical, with BCG)" ;
  onco:approval "US 2024: BCG-unresponsive NMIBC with CIS ± papillary tumours, with BCG", "EU 2026: BCG-unresponsive NMIBC with CIS, with BCG; 16 Feb 2026 (conditional)" ;
  onco:cancers <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/non-muscle-invasive-bladder-cancer/> ;
  onco:technologies <https://onco.cc/technologies/cytokine-therapy/>, <https://onco.cc/technologies/bcg-and-intravesical-therapy/> ;
  onco:companies <https://onco.cc/companies/immunitybio/> ;
  onco:terms <https://onco.cc/terms/bcg-unresponsive/> ;
  onco:trials <https://onco.cc/trials/quilt-3-032/>, <https://onco.cc/trials/nct06710288/>, <https://onco.cc/trials/nct03228667/>, <https://onco.cc/trials/nct06061809/>, <https://onco.cc/trials/nct06745908/>, <https://onco.cc/trials/nct04390399/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-chamie-nejm-evid/> .