# OnCo record non-inferiority-margin (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/non-inferiority-margin/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "non-inferiority-margin" ;
  schema:name "Non-inferiority margin and equivalence trials"@en ;
  schema:alternateName "non-inferiority margin"@en, "noninferiority margin"@en, "the margin"@en, "pre-specified margin"@en, "prespecified margin"@en, "equivalence margin"@en, "equivalence design"@en, "bioequivalence"@en, "biosimilar equivalence"@en, "upper bound of the confidence interval"@en, "acceptable loss of efficacy"@en, "absolute margin"@en, "relative margin"@en, "non-inferiority boundary"@en, "noninferiority boundary"@en ;
  schema:description "The margin is the amount of benefit a trial is allowed to lose and still call the new treatment good enough; it is chosen before the trial starts, and where it is set decides what the result means."@en ;
  schema:url <https://onco.cc/terms/non-inferiority-margin/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Non-inferiority_trial> ;
  schema:citation <https://en.wikipedia.org/wiki/Non-inferiority_trial>, <https://www.fda.gov/regulatory-information/search-fda-guidance-documents/non-inferiority-clinical-trials>, <https://www.ich.org/page/efficacy-guidelines> ;
  onco:related <https://onco.cc/terms/non-inferiority/>, <https://onco.cc/terms/randomised-trial/>, <https://onco.cc/terms/intention-to-treat/>, <https://onco.cc/terms/confidence-interval/>, <https://onco.cc/terms/de-escalation/>, <https://onco.cc/terms/hypofractionation/>, <https://onco.cc/terms/trial-failure-modes/>, <https://onco.cc/terms/estimand/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:trials <https://onco.cc/trials/persephone/>, <https://onco.cc/trials/fast-forward/>, <https://onco.cc/trials/pace-b/>, <https://onco.cc/trials/tailorx/>, <https://onco.cc/trials/dynamic/>, <https://onco.cc/trials/convert/>, <https://onco.cc/trials/sano/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/> .