# OnCo record npm1-mutation (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/npm1-mutation/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "npm1-mutation" ;
  schema:name "NPM1 mutation"@en ;
  schema:alternateName "NPM1 mutation"@en, "NPM1-mutated AML"@en, "NPM1c"@en, "mutated NPM1"@en, "NPM1 type A"@en, "NPM1mut"@en ;
  schema:description "NPM1 mutations, found in about a third of adult acute myeloid leukaemias, misplace the nucleophosmin protein into the cytoplasm. They mean a better outlook without FLT3-ITD, a sensitive MRD marker, and since 2025 a targeted menin inhibitor."@en ;
  schema:url <https://onco.cc/biomarkers/npm1-mutation/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b650f696-3391-4274-8b55-a5f5e9d04769>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6eb3cdbc-0e74-477d-82d6-3bb172d3f63f> ;
  onco:tag "biomarker", "aml" ;
  onco:related <https://onco.cc/biomarkers/flt3-itd/>, <https://onco.cc/biomarkers/idh1-r132/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-npm1-kmt2a/> ;
  onco:drugs <https://onco.cc/drugs/ziftomenib/>, <https://onco.cc/drugs/revumenib/> ;
  onco:terms <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/molecular-response/> .