# OnCo record npm1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/npm1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "npm1" ;
  schema:name "NPM1 mutation"@en ;
  schema:description "NPM1 is the most common mutation in adult leukaemia. It moves a nuclear protein into the cytoplasm and, it turns out, makes the leukaemia dependent on menin."@en ;
  schema:url <https://onco.cc/targets/npm1/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Nucleophosmin>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7910>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000181163>, <https://www.uniprot.org/uniprotkb/P06748/entry>, <https://www.ncbi.nlm.nih.gov/gene/4869> ;
  schema:citation <https://en.wikipedia.org/wiki/Nucleophosmin> ;
  onco:tag "driver", "mrd-marker" ;
  schema:alternateName "NPM1" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1986"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/menin/>, <https://onco.cc/targets/flt3/>, <https://onco.cc/biomarkers/npm1-mutation/> ;
  onco:cancers <https://onco.cc/cancers/aml/> ;
  onco:drugs <https://onco.cc/drugs/revumenib/>, <https://onco.cc/drugs/ziftomenib/> ;
  onco:terms <https://onco.cc/terms/mrd-negative-cr/> .