# OnCo record nras (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/nras/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "nras" ;
  schema:name "NRAS"@en ;
  schema:alternateName "N-ras"@en, "NRAS proto-oncogene, GTPase"@en, "NRAS" ;
  schema:description "NRAS is one of the three RAS switch proteins that pass growth signals into the cell. When a mutation jams it on, as in a share of melanomas, the cell keeps dividing; today's drugs reach it indirectly through MEK or RAF, and pan-RAS inhibitors that bind the active form are in trials."@en ;
  schema:url <https://onco.cc/targets/nras/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7989>, <https://www.uniprot.org/uniprotkb/P01111/entry>, <https://www.ncbi.nlm.nih.gov/gene/4893> ;
  onco:tag "wave5-target" ;
  onco:targetClass "oncogene" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7989>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000213281>, <https://www.uniprot.org/uniprotkb/P01111/entry>, <https://www.ncbi.nlm.nih.gov/gene/4893> ;
  onco:related <https://onco.cc/drugs/tunlametinib/>, <https://onco.cc/drugs/naporafenib/>, <https://onco.cc/drugs/cetuximab/>, <https://onco.cc/drugs/tempus-xt-cdx/>, <https://onco.cc/drugs/lenzilumab/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/mek/>, <https://onco.cc/targets/nf1/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/cmml/> ;
  onco:technologies <https://onco.cc/technologies/kras-inhibitors/> ;
  onco:drugs <https://onco.cc/drugs/jyp0015/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/melanoma-signalling/>, <https://onco.cc/pathways/colorectal-cancer-signalling/> .