# OnCo record nst-628 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/nst-628/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "nst-628" ;
  schema:name "NST-628"@en ;
  schema:description "NST-628 is an experimental oral small-molecule molecular glue from Nested Therapeutics, in phase 1 trials for MAPK pathway-mutated or -dependent advanced solid tumours, melanoma and non-small cell lung cancer and other cancers."@en ;
  schema:url <https://onco.cc/drugs/nst-628/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://nestedtx.com/>, <https://nestedtx.com/>, <https://clinicaltrials.gov/api/v2/studies/NCT06326411>, <https://clinicaltrials.gov/api/v2/studies/NCT07784985>, <https://clinicaltrials.gov/search?intr=NST-628> ;
  onco:status "phase-1" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:modality "Oral small-molecule molecular glue" ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/brain-tumours/> ;
  onco:targets <https://onco.cc/targets/mek/> ;
  onco:companies <https://onco.cc/companies/nested-therapeutics/> ;
  onco:trials <https://onco.cc/trials/nct06326411/>, <https://onco.cc/trials/nct07784985/> .