# OnCo record ntrk-fusion (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/ntrk-fusion/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "ntrk-fusion" ;
  schema:name "NTRK1/2/3 gene fusion"@en ;
  schema:alternateName "NTRK fusion"@en, "NTRK gene fusion"@en, "TRK fusion"@en, "NTRK1 fusion"@en, "NTRK2 fusion"@en, "NTRK3 fusion"@en, "ETV6-NTRK3"@en, "ETV6::NTRK3"@en, "TRK fusion cancer"@en, "NTRK"@en ;
  schema:description "An NTRK fusion joins one of three TRK kinase genes to a partner and drives cancers from infant fibrosarcoma to salivary and thyroid tumours, rare in common cancers but near-universal in a few rare ones. Larotrectinib, entrectinib and repotrectinib are approved for it regardless of tumour type."@en ;
  schema:url <https://onco.cc/biomarkers/ntrk-fusion/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0c8ca614-58b2-4aa4-83d3-0387a8f782fd>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7c71b0c-2549-4495-86b6-c2807fa54908> ;
  onco:tag "biomarker", "fusion" ;
  onco:related <https://onco.cc/biomarkers/ret-fusion/>, <https://onco.cc/biomarkers/ros1-fusion/>, <https://onco.cc/biomarkers/alk-fusion/> ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/thyroid/>, <https://onco.cc/cancers/salivary-gland/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/nsclc/> ;
  onco:drugs <https://onco.cc/drugs/larotrectinib/>, <https://onco.cc/drugs/entrectinib/>, <https://onco.cc/drugs/repotrectinib/>, <https://onco.cc/drugs/foundationone-cdx/>, <https://onco.cc/drugs/trusight-oncology-comprehensive/> ;
  onco:terms <https://onco.cc/terms/gene-fusion/>, <https://onco.cc/terms/tumour-agnostic/>, <https://onco.cc/terms/tki-term/> .