# OnCo record ofatumumab (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ofatumumab/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "ofatumumab" ;
  schema:name "Ofatumumab"@en ;
  schema:alternateName "Kesimpta (multiple sclerosis formulation)"@en, "Arzerra" ;
  schema:description "Ofatumumab (Arzerra) is a fully human anti-CD20 antibody for chronic lymphocytic leukaemia, used with chlorambucil in untreated patients or alone after other drugs have failed; the same molecule is sold as Kesimpta for multiple sclerosis."@en ;
  schema:url <https://onco.cc/drugs/ofatumumab/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Ofatumumab> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ofatumumab>, <https://www.cancer.gov/about-cancer/treatment/drugs/ofatumumab> ;
  onco:status "approved" ;
  onco:tag "nci-list" ;
  onco:modality "Monoclonal antibody (anti-CD20, fully human IgG1)" ;
  onco:approval "US 2009: CLL refractory to fludarabine and alemtuzumab (accelerated)", "US 2014: Previously untreated CLL with chlorambucil; later extended treatment and relapsed CLL with fludarabine and cyclophosphamide", "EU 2010: CLL refractory to fludarabine and alemtuzumab (conditional; authorisation since withdrawn)" ;
  onco:acceleratedApproval "US 2009-10-26: Chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab" ;
  onco:acceleratedApprovalConfirmed "US 2014-04-17: Chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab" ;
  onco:related <https://onco.cc/drugs/rituximab/>, <https://onco.cc/drugs/obinutuzumab/> ;
  onco:cancers <https://onco.cc/cancers/cll/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/> ;
  onco:targets <https://onco.cc/targets/cd20/> ;
  onco:companies <https://onco.cc/companies/novartis/>, <https://onco.cc/companies/genmab/> .