# OnCo record oprm1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/oprm1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "oprm1" ;
  schema:name "Mu-opioid receptor"@en ;
  schema:description "The mu-opioid receptor is the target of morphine and the other strong opioids that control most severe cancer pain; the same receptor in the gut causes opioid constipation, which methylnaltrexone and naloxegol relieve by blocking it outside the brain."@en ;
  schema:url <https://onco.cc/targets/oprm1/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Μ-opioid_receptor>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8156>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000112038>, <https://www.uniprot.org/uniprotkb/P35372/entry>, <https://www.ncbi.nlm.nih.gov/gene/4988> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P35372/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8156>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL233> ;
  onco:tag "chembl-gap" ;
  schema:alternateName "OPRM1" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1994"^^xsd:gYear ;
  onco:drugs <https://onco.cc/drugs/methylnaltrexone/> ;
  onco:terms <https://onco.cc/technologies/palliative-care/> .