# OnCo record optic-pathway-glioma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/optic-pathway-glioma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "optic-pathway-glioma" ;
  schema:name "Optic pathway glioma"@en ;
  schema:alternateName "Optic nerve glioma"@en, "Optic glioma"@en, "NF1-associated optic pathway glioma"@en, "Hypothalamic-chiasmatic glioma"@en, "NF1-associated optic pathway glioma (paediatric low-grade glioma)"@en ;
  schema:description "Optic pathway glioma is a slow-growing childhood brain tumour of the nerves that carry sight, often in children with neurofibromatosis type 1. It rarely kills but can take away vision, so treatment aims to preserve sight: watching if stable, chemotherapy such as carboplatin and vincristine if vision is threatened, or the MEK-blocking tablet selumetinib, with radiotherapy avoided in young children."@en ;
  schema:url <https://onco.cc/cancers/optic-pathway-glioma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Optic_nerve_glioma> ;
  schema:citation <https://www.cancer.gov/types/brain/patient/childhood-glioma-astrocytoma>, <https://doi.org/10.1212/01.wnl.0000435745.95155.b8>, <https://doi.org/10.1002/cncr.29649>, <https://doi.org/10.1016/s1470-2045(19)30277-3> ;
  onco:tag "subtype-page", "wave4", "rare" ;
  onco:related <https://onco.cc/cancers/paediatric-low-grade-glioma/>, <https://onco.cc/cancers/brain-tumours/>, <https://onco.cc/cancers/childhood-cancers/>, <https://onco.cc/cancers/vestibular-schwannoma/> ;
  onco:targets <https://onco.cc/targets/nf1/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/selumetinib/>, <https://onco.cc/drugs/tovorafenib/>, <https://onco.cc/drugs/dabrafenib/>, <https://onco.cc/drugs/trametinib/> ;
  onco:standardOfCare <https://onco.cc/cancers/paediatric-low-grade-glioma/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/selumetinib/>, <https://onco.cc/drugs/tovorafenib/>, <https://onco.cc/drugs/dabrafenib/>, <https://onco.cc/drugs/trametinib/> .