# OnCo record opus (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/opus/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "opus", "NCT00125034" ;
  schema:name "OPUS"@en ;
  schema:description "The oxaliplatin companion to CRYSTAL. It confirmed that the EGFR antibody only works when KRAS is normal."@en ;
  schema:url <https://onco.cc/trials/opus/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00125034>, <https://doi.org/10.1093/annonc/mdq632> ;
  onco:status "positive" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/braf/> ;
  onco:drugs <https://onco.cc/drugs/cetuximab/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/oxaliplatin/> ;
  onco:companies <https://onco.cc/companies/merck-kgaa/> ;
  onco:trials <https://onco.cc/trials/crystal-fire3/>, <https://onco.cc/trials/prime/> .