# OnCo record osilodrostat (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/osilodrostat/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "osilodrostat" ;
  schema:name "Osilodrostat"@en ;
  schema:alternateName "LCI699"@en, "Isturisa" ;
  schema:description "Osilodrostat is a twice-daily tablet that stops the adrenal glands making cortisol. It controls Cushing's disease caused by a pituitary tumour when surgery has failed or is not possible, normalising cortisol in most patients."@en ;
  schema:url <https://onco.cc/drugs/osilodrostat/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Osilodrostat> ;
  schema:citation <https://en.wikipedia.org/wiki/Osilodrostat> ;
  onco:status "approved" ;
  onco:tag "subtype-drugs-wave" ;
  onco:modality "Oral 11-beta-hydroxylase (CYP11B1) inhibitor" ;
  onco:approval "EU 2020: Endogenous Cushing's syndrome in adults", "US 2020: Cushing's disease in adults for whom pituitary surgery is not an option or has not been curative" ;
  onco:related <https://onco.cc/drugs/metyrapone/> ;
  onco:cancers <https://onco.cc/cancers/pituitary-tumours/> ;
  onco:companies <https://onco.cc/companies/recordati/> .