# OnCo record pacritinib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pacritinib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pacritinib" ;
  schema:name "Pacritinib"@en ;
  schema:description "The JAK inhibitor for myelofibrosis patients whose platelet counts are too low for ruxolitinib."@en ;
  schema:url <https://onco.cc/drugs/pacritinib/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pacritinib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q3888693> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=pacritinib> ;
  onco:status "approved" ;
  onco:tag "gap-fill" ;
  onco:modality "Small-molecule JAK2/IRAK1/ACVR1 inhibitor" ;
  schema:alternateName "Vonjo" ;
  onco:approval "US 2022: Intermediate/high-risk myelofibrosis with platelets <50×10⁹/L" ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/primary-myelofibrosis/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/jak2/>, <https://onco.cc/targets/flt3/>, <https://onco.cc/targets/acvr1/> ;
  onco:companies <https://onco.cc/companies/sobi/> ;
  onco:trials <https://onco.cc/trials/nct07033598/> .