# OnCo record pada-1 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/pada-1/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "pada-1", "NCT03079011" ;
  schema:name "PADA-1"@en ;
  schema:alternateName "PADA 1"@en, "UCBG3-05"@en ;
  schema:description "A French trial that showed, for the first time in a randomised study, that changing hormone therapy when a resistance mutation appears in the blood, before scans change, keeps breast cancer controlled for longer."@en ;
  schema:url <https://onco.cc/trials/pada-1/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03079011>, <https://doi.org/10.1016/S1470-2045(22)00555-1> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2017-03-22" ;
  onco:related <https://onco.cc/trials/serena-6/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/> ;
  onco:drugs <https://onco.cc/drugs/palbociclib/>, <https://onco.cc/drugs/fulvestrant/>, <https://onco.cc/drugs/letrozole/> ;
  onco:companies <https://onco.cc/companies/unicancer/> ;
  onco:terms <https://onco.cc/terms/esr1-mutation/>, <https://onco.cc/terms/ctdna/> ;
  onco:people <https://onco.cc/people/francois-clement-bidard/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-bidard-pada-1-lancet-oncol-2022/> .