# OnCo record palonosetron (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/palonosetron/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "palonosetron" ;
  schema:name "Palonosetron"@en ;
  schema:alternateName "Posfrea"@en, "Aloxi" ;
  schema:description "Palonosetron (Aloxi) is a long-acting anti-sickness injection given once before chemotherapy; a single dose covers both the first day and the delayed nausea that follows."@en ;
  schema:url <https://onco.cc/drugs/palonosetron/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Palonosetron> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=palonosetron>, <https://www.cancer.gov/about-cancer/treatment/drugs/palonosetronhydrochloride>, <https://www.ema.europa.eu/en/medicines/human/EPAR/aloxi> ;
  onco:status "approved" ;
  onco:tag "nci-list", "supportive" ;
  onco:modality "Second-generation 5-HT3 receptor antagonist (antiemetic)" ;
  onco:approval "US 2003: Acute and delayed nausea and vomiting with moderately emetogenic chemotherapy; acute with highly emetogenic chemotherapy (paediatric from 1 month added 2014)", "EU 2005: Prevention of chemotherapy-induced nausea and vomiting (Aloxi)" ;
  onco:related <https://onco.cc/drugs/netupitant-palonosetron/>, <https://onco.cc/drugs/ondansetron/> ;
  onco:technologies <https://onco.cc/technologies/antiemetic-therapy/> ;
  onco:companies <https://onco.cc/companies/helsinn/>, <https://onco.cc/companies/eisai/> ;
  onco:trials <https://onco.cc/trials/nct06904235/> .