# OnCo record pancreatic (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/pancreatic/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "pancreatic" ;
  schema:name "Pancreatic ductal adenocarcinoma"@en ;
  schema:description "Almost every pancreatic tumour carries a KRAS mutation, and for the first time drugs against it work: daraxonrasib nearly doubled survival in previously treated disease in 2026. Pancreatic cancer has been the hardest common cancer to treat once advanced; that is what is starting to change."@en ;
  schema:url <https://onco.cc/cancers/pancreatic/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pancreatic_cancer> ;
  owl:sameAs <http://www.wikidata.org/entity/Q212961> ;
  schema:citation <https://en.wikipedia.org/wiki/Pancreatic_cancer>, <https://www.nice.org.uk/guidance/ng85/chapter/Recommendations>, <https://www.natcan.org.uk/reports/npaca-state-of-the-nation-report-2026/>, <https://www.pancreaticcancer.org.uk/>, <https://www.nhs.uk/conditions/pancreatic-cancer/symptoms/>, <https://www.nhs.uk/conditions/pancreatic-cancer/tests-and-next-steps/>, <https://www.nhs.uk/conditions/pancreatic-cancer/treatment/>, <https://www.nhs.uk/conditions/pancreatic-cancer/help-and-support/>, <https://www.nice.org.uk/guidance/ng85/chapter/Recommendations>, <https://www.nice.org.uk/guidance/ta476/chapter/1-Recommendations>, <https://www.nice.org.uk/guidance/ta440/chapter/1-Recommendations>, <https://www.nice.org.uk/guidance/terminated/ta750>, <https://www.pancreaticcancer.org.uk/information/just-diagnosed-with-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/just-diagnosed-with-pancreatic-cancer/if-you-cant-have-surgery-inoperable-cancer/>, <https://www.pancreaticcancer.org.uk/information/treatments-for-pancreatic-cancer/surgery-for-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/treatments-for-pancreatic-cancer/chemotherapy/how-is-chemotherapy-used-for-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/managing-symptoms-and-side-effects/diet-and-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/managing-symptoms-and-side-effects/diet-and-pancreatic-cancer/pancreatic-enzyme-replacement-therapy-pert/how-do-i-take-pancreatic-enzyme-replacement-therapy-if-i-have-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/managing-symptoms-and-side-effects/diabetes-with-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/managing-symptoms-and-side-effects/managing-pancreatic-cancer-pain/>, <https://www.pancreaticcancer.org.uk/information/managing-symptoms-and-side-effects/managing-jaundice-if-you-have-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/dealing-with-pancreatic-cancer/dealing-with-the-emotional-impact-of-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/daily-life-with-pancreatic-cancer/work-and-money/>, <https://www.pancreaticcancer.org.uk/support-for-you/information-for-family-members/>, <https://www.pancreaticcancer.org.uk/information/family-history-of-pancreatic-cancer/>, <https://www.pancreaticcancer.org.uk/information/treatments-for-pancreatic-cancer/current-developments-in-pancreatic-cancer-treatment/>, <https://www.macmillan.org.uk/cancer-information-and-support/pancreatic-cancer/controlling-symptoms-of-pancreatic-cancer>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/chemotherapy-for-pancreatic-cancer>, <https://www.macmillan.org.uk/cancer-information-and-support/pancreatic-cancer/types-of-surgery-for-pancreatic-cancer>, <https://www.macmillan.org.uk/cancer-information-and-support/treatment/your-treatment-options/questions-to-ask-your-healthcare-team>, <https://www.macmillan.org.uk/information-and-support/coping/advanced-cancer>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/olaparib>, <https://www.macmillan.org.uk/cancer-information-and-support/worried-about-cancer/causes-and-risk-factors/brca-gene>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/treatment/treatment-decisions>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/treatment/surgery>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/treatment/chemotherapy>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/treatment/about-radiotherapy>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/treatment/controlling-symptoms>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/treatment/follow-up-appointment>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/living-with/diet>, <https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/living-with/coping>, <https://www.esmo.org/for-patients/patient-guides/pancreatic-cancer>, <https://www.mariecurie.org.uk/help/support/diagnosed/recent-diagnosis/palliative-care-end-of-life-care>, <https://doi.org/10.1056/NEJMoa1011923>, <https://doi.org/10.1056/NEJMoa1304369>, <https://doi.org/10.1016/S0140-6736(23)01366-1>, <https://doi.org/10.1056/NEJMoa1809775>, <https://doi.org/10.1016/S0140-6736(16)32409-6>, <https://doi.org/10.1056/NEJMoa1903387>, <https://doi.org/10.1200/JCO.21.02233>, <https://doi.org/10.1200/JCO.2010.32.2750>, <https://doi.org/10.1016/j.pan.2018.10.010>, <https://doi.org/10.1136/bmjgast-2021-000643>, <https://doi.org/10.1016/j.surg.2018.01.024>, <https://doi.org/10.1200/JCO.20.00611>, <https://www.nhs.uk/tests-and-treatments/clinical-trials/>, <https://www.nhs.uk/tests-and-treatments/genetic-and-genomic-testing/>, <https://www.macmillan.org.uk/cancer-information-and-support/impacts-of-cancer/sepsis>, <https://www.macmillan.org.uk/cancer-information-and-support/supporting-someone/looking-after-someone-with-cancer> ;
  onco:tag "gi", "spike" ;
  onco:related <https://onco.cc/roadmaps/kras-roadmap/>, <https://onco.cc/roadmaps/early-detection-roadmap/>, <https://onco.cc/collections/pancan/>, <https://onco.cc/ideas/idea-drugging-myc/>, <https://onco.cc/ideas/idea-nerve-tumour-blockade/> ;
  onco:technologies <https://onco.cc/technologies/kras-inhibitors/>, <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/ttfields/>, <https://onco.cc/technologies/fapi-pet/>, <https://onco.cc/technologies/mced/>, <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/irreversible-electroporation/>, <https://onco.cc/technologies/omega3-epa-cachexia/>, <https://onco.cc/technologies/mistletoe-extracts/>, <https://onco.cc/technologies/gerson-therapy-detox-regimens/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/sbrt/>, <https://onco.cc/technologies/mr-linac/>, <https://onco.cc/technologies/shared-antigen-vaccine/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/technologies/pancreatic-surveillance/>, <https://onco.cc/technologies/pdac-organoid-pharmacotyping/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/biliary-stenting-drainage/>, <https://onco.cc/technologies/palliative-care/>, <https://onco.cc/technologies/pain-management/>, <https://onco.cc/technologies/oncology-nutrition/>, <https://onco.cc/technologies/enteral-parenteral-nutrition/>, <https://onco.cc/technologies/prehabilitation/>, <https://onco.cc/technologies/cancer-associated-thrombosis/>, <https://onco.cc/technologies/multidisciplinary-tumour-board/>, <https://onco.cc/technologies/psycho-oncology/>, <https://onco.cc/technologies/peer-support-groups/>, <https://onco.cc/technologies/cbt-fatigue-distress/>, <https://onco.cc/technologies/exercise-during-chemotherapy/>, <https://onco.cc/technologies/palliative-radiotherapy/>, <https://onco.cc/technologies/endoscopic-ultrasound-systems/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/brca/>, <https://onco.cc/targets/cldn18-2/>, <https://onco.cc/targets/fap/>, <https://onco.cc/targets/mesothelin/>, <https://onco.cc/targets/her3/>, <https://onco.cc/targets/ntrk/>, <https://onco.cc/targets/parp/> ;
  onco:drugs <https://onco.cc/drugs/catumaxomab/>, <https://onco.cc/drugs/tegafur-gimeracil-oteracil/> ;
  onco:companies <https://onco.cc/companies/marker-therapeutics/>, <https://onco.cc/companies/orion-orion-pharma/>, <https://onco.cc/companies/crinetics-pharmaceuticals/>, <https://onco.cc/companies/oncolytics-biotech/>, <https://onco.cc/companies/shenzhen-ionova-life-sciences/>, <https://onco.cc/companies/ascentawits-pharmaceuticals/>, <https://onco.cc/companies/cebiotex/>, <https://onco.cc/companies/civatech-oncology/>, <https://onco.cc/companies/mbrace-therapeutics/>, <https://onco.cc/companies/molecular-partners/>, <https://onco.cc/companies/revolution-medicines/>, <https://onco.cc/companies/ipsen/>, <https://onco.cc/companies/novocure/>, <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/elicio-therapeutics/>, <https://onco.cc/companies/astrazeneca/>, <https://onco.cc/companies/carsgen/>, <https://onco.cc/companies/bms/> ;
  onco:institutions <https://onco.cc/institutions/pancreatic-cancer-uk/>, <https://onco.cc/institutions/pancreatic-cancer-action/>, <https://onco.cc/institutions/wolfson-wohl-cancer-research-centre/>, <https://onco.cc/institutions/liverpool-hpb-centre/>, <https://onco.cc/institutions/glasgow-royal-infirmary/>, <https://onco.cc/institutions/hull-castle-hill/>, <https://onco.cc/institutions/royal-stoke-uhnm/>, <https://onco.cc/institutions/uhcw-coventry/>, <https://onco.cc/institutions/royal-surrey-guildford/>, <https://onco.cc/institutions/royal-blackburn-elht/>, <https://onco.cc/institutions/ninewells-dundee/>, <https://onco.cc/institutions/aberdeen-royal-infirmary/>, <https://onco.cc/institutions/raigmore-inverness/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/ddr/>, <https://onco.cc/pathways/pancreatic-cancer-signalling/>, <https://onco.cc/pathways/emt/> ;
  onco:terms <https://onco.cc/terms/ca19-9/>, <https://onco.cc/terms/desmoplasia/>, <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/hazard-ratio/>, <https://onco.cc/terms/resectability/>, <https://onco.cc/terms/whipple/>, <https://onco.cc/terms/obstructive-jaundice/>, <https://onco.cc/terms/stent-or-bypass-for-jaundice/>, <https://onco.cc/terms/biliary-stent-problems/>, <https://onco.cc/terms/acute-cholangitis/>, <https://onco.cc/terms/jaundice-and-itch-biliary/>, <https://onco.cc/terms/duodenal-stenting-gastric-outlet/>, <https://onco.cc/terms/cachexia/>, <https://onco.cc/terms/nutrition-impact-symptoms/>, <https://onco.cc/terms/sarcopenia/>, <https://onco.cc/terms/peripheral-neuropathy/>, <https://onco.cc/terms/neutropenia/>, <https://onco.cc/terms/febrile-neutropenia/>, <https://onco.cc/terms/hand-foot-syndrome/>, <https://onco.cc/terms/mucositis/>, <https://onco.cc/terms/cancer-related-fatigue/>, <https://onco.cc/terms/vte/>, <https://onco.cc/terms/central-venous-access/>, <https://onco.cc/terms/performance-status/>, <https://onco.cc/terms/financial-toxicity/>, <https://onco.cc/terms/emotional-support-cancer-uk/>, <https://onco.cc/terms/malnutrition-screening/> ;
  onco:trials <https://onco.cc/trials/mountaintap-30/>, <https://onco.cc/trials/nct06608927/>, <https://onco.cc/trials/nct07262567/>, <https://onco.cc/trials/nct07409272/>, <https://onco.cc/trials/nct07522073/>, <https://onco.cc/trials/nct06079346/>, <https://onco.cc/trials/nct07079228/>, <https://onco.cc/trials/nct05254171/>, <https://onco.cc/trials/nct07562152/>, <https://onco.cc/trials/g-hope-002/>, <https://onco.cc/trials/nct01954992/>, <https://onco.cc/trials/notable-trial/>, <https://onco.cc/trials/nct07491445/>, <https://onco.cc/trials/nct07219238/>, <https://onco.cc/trials/nct07805954/>, <https://onco.cc/trials/nct07252232/>, <https://onco.cc/trials/nct07621718/>, <https://onco.cc/trials/nct04969731/>, <https://onco.cc/trials/nct06361888/>, <https://onco.cc/trials/nct03257033/>, <https://onco.cc/trials/nct06953999/>, <https://onco.cc/trials/nct07165886/>, <https://onco.cc/trials/nct06784752/>, <https://onco.cc/trials/nct05653453/>, <https://onco.cc/trials/nct03972488/>, <https://onco.cc/trials/nct06861088/>, <https://onco.cc/trials/nct07232875/>, <https://onco.cc/trials/nct06752811/>, <https://onco.cc/trials/nct07087054/>, <https://onco.cc/trials/nct07823049/>, <https://onco.cc/trials/nct05884255/>, <https://onco.cc/trials/nct07238283/>, <https://onco.cc/trials/nct03899636/>, <https://onco.cc/trials/rasolute-302/>, <https://onco.cc/trials/napoli-3/>, <https://onco.cc/trials/prodige-24/>, <https://onco.cc/trials/preopanc/>, <https://onco.cc/trials/polo/>, <https://onco.cc/trials/panova-3/>, <https://onco.cc/trials/amplify-7p/>, <https://onco.cc/trials/europac/>, <https://onco.cc/trials/precision-panc/> ;
  onco:people <https://onco.cc/people/randy-pausch/>, <https://onco.cc/people/daniel-von-hoff/>, <https://onco.cc/people/andrew-biankin/>, <https://onco.cc/people/paula-ghaneh/>, <https://onco.cc/people/daniel-palmer/>, <https://onco.cc/people/chris-halloran/>, <https://onco.cc/people/bill-greenhalf/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-burris-gemcitabine-pancreatic-jco-1997/>, <https://onco.cc/key-papers/paper-rahib-projecting-cancer-deaths-2030-cancerres-2014/> ;
  onco:journals <https://onco.cc/journals/journal-of-gastrointestinal-cancer/> ;
  onco:pipeline <https://onco.cc/drugs/daraxonrasib/>, <https://onco.cc/drugs/autogene-cevumeran/>, <https://onco.cc/drugs/cmg901/>, <https://onco.cc/drugs/fap-2286/>, <https://onco.cc/technologies/fapi-pet/>, <https://onco.cc/drugs/galleri/>, <https://onco.cc/drugs/satricabtagene-autoleucel/>, <https://onco.cc/drugs/in10018/>, <https://onco.cc/drugs/lm-108/>, <https://onco.cc/drugs/navlimetostat/>, <https://onco.cc/drugs/quemliclustat/>, <https://onco.cc/drugs/gfh375/>, <https://onco.cc/drugs/gotistobart/>, <https://onco.cc/drugs/sitneprotafib/>, <https://onco.cc/drugs/setidegrasib/>, <https://onco.cc/drugs/incb161734/>, <https://onco.cc/drugs/trabedersen/>, <https://onco.cc/drugs/qls31905/>, <https://onco.cc/drugs/ivospemin/>, <https://onco.cc/drugs/atebimetinib/>, <https://onco.cc/drugs/ibi343/>, <https://onco.cc/drugs/vs-7375/>, <https://onco.cc/drugs/tng462/>, <https://onco.cc/drugs/xnw27011/>, <https://onco.cc/drugs/e-edv-d682/>, <https://onco.cc/drugs/azd4360/>, <https://onco.cc/drugs/mavrostobart/>, <https://onco.cc/drugs/jk08/>, <https://onco.cc/drugs/jyp0015/>, <https://onco.cc/drugs/spevatamig/>, <https://onco.cc/drugs/azd5863/>, <https://onco.cc/drugs/ct3001/>, <https://onco.cc/drugs/ponsegromab/>, <https://onco.cc/drugs/jmt203/>, <https://onco.cc/drugs/lp-184/>, <https://onco.cc/drugs/pbp1510/>, <https://onco.cc/drugs/mitazalimab/>, <https://onco.cc/drugs/vb15010/>, <https://onco.cc/drugs/tqb2868/>, <https://onco.cc/drugs/nuv-1511/>, <https://onco.cc/drugs/zoldonrasib/>, <https://onco.cc/drugs/elironrasib/>, <https://onco.cc/drugs/mrtx1133/>, <https://onco.cc/drugs/eli-002-7p/>, <https://onco.cc/trials/rasolute-302/>, <https://onco.cc/pairings/g12d-plus-pan-ras/>, <https://onco.cc/technologies/pancreatic-surveillance/>, <https://onco.cc/technologies/pdac-organoid-pharmacotyping/>, <https://onco.cc/ideas/idea-ras-inhibitor-neoadjuvant-pdac/>, <https://onco.cc/ideas/idea-mced-new-onset-diabetes/>, <https://onco.cc/ideas/idea-shared-kras-vaccine-adjuvant/>, <https://onco.cc/ideas/idea-fap-theranostics-pancancer/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:standardOfCare <https://onco.cc/technologies/pancreatic-surveillance/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/technologies/mri/>, <https://onco.cc/trials/precede/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/trials/prodige-24/>, <https://onco.cc/trials/preopanc/>, <https://onco.cc/technologies/robotic-surgery/>, <https://onco.cc/trials/panova-3/>, <https://onco.cc/drugs/optune/>, <https://onco.cc/drugs/gemcitabine-nab-paclitaxel/>, <https://onco.cc/technologies/sbrt/>, <https://onco.cc/drugs/nalirifox/>, <https://onco.cc/trials/napoli-3/>, <https://onco.cc/trials/polo/>, <https://onco.cc/drugs/zoldonrasib/>, <https://onco.cc/trials/rasolute-302/>, <https://onco.cc/drugs/daraxonrasib/>, <https://onco.cc/terms/resectability/>, <https://onco.cc/terms/whipple/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/trials/preopanc/>, <https://onco.cc/trials/espac-5/>, <https://onco.cc/technologies/prehabilitation/>, <https://onco.cc/cancers/resectable-pdac/>, <https://onco.cc/cancers/borderline-resectable-pdac/>, <https://onco.cc/technologies/multidisciplinary-tumour-board/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/drugs/gemcitabine-nab-paclitaxel/>, <https://onco.cc/drugs/nalirifox/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/trials/napoli-3/>, <https://onco.cc/terms/peripheral-neuropathy/>, <https://onco.cc/terms/performance-status/>, <https://onco.cc/cancers/metastatic-pdac/>, <https://onco.cc/cancers/locally-advanced-pdac/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/trials/prodige-24/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/terms/whipple/>, <https://onco.cc/terms/ca19-9/>, <https://onco.cc/cancers/resectable-pdac/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/targets/brca/>, <https://onco.cc/drugs/olaparib/>, <https://onco.cc/trials/polo/>, <https://onco.cc/cancers/brca-palb2-pdac/>, <https://onco.cc/drugs/folfirinox/>, <https://onco.cc/technologies/biliary-stenting-drainage/>, <https://onco.cc/terms/stent-or-bypass-for-jaundice/>, <https://onco.cc/terms/biliary-stent-problems/>, <https://onco.cc/terms/acute-cholangitis/>, <https://onco.cc/terms/obstructive-jaundice/>, <https://onco.cc/terms/duodenal-stenting-gastric-outlet/>, <https://onco.cc/technologies/pain-management/>, <https://onco.cc/technologies/palliative-care/>, <https://onco.cc/technologies/palliative-radiotherapy/>, <https://onco.cc/technologies/endoscopic-ultrasound-systems/>, <https://onco.cc/terms/cachexia/>, <https://onco.cc/technologies/oncology-nutrition/>, <https://onco.cc/terms/whipple/>, <https://onco.cc/terms/enzyme/>, <https://onco.cc/terms/nutrition-impact-symptoms/>, <https://onco.cc/terms/cachexia/>, <https://onco.cc/technologies/oncology-nutrition/>, <https://onco.cc/technologies/enteral-parenteral-nutrition/>, <https://onco.cc/terms/malnutrition-screening/>, <https://onco.cc/terms/duodenal-stenting-gastric-outlet/>, <https://onco.cc/drugs/daraxonrasib/>, <https://onco.cc/trials/rasolute-302/>, <https://onco.cc/trials/precede/>, <https://onco.cc/collections/pancan/>, <https://onco.cc/technologies/palliative-care/>, <https://onco.cc/technologies/pain-management/>, <https://onco.cc/technologies/psycho-oncology/>, <https://onco.cc/terms/emotional-support-cancer-uk/>, <https://onco.cc/technologies/cbt-fatigue-distress/> .