# OnCo record paper-augment-101-revumenib-menin-nature-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-augment-101-revumenib-menin-nature-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-augment-101-revumenib-menin-nature-2023" ;
  schema:name "AUGMENT-101: revumenib, the first menin inhibitor, in relapsed leukaemias driven by KMT2A rearrangement or NPM1 mutation"@en ;
  schema:description "Blocking menin, a scaffold protein the leukaemia depends on, produced remissions in heavily pretreated patients with KMT2A-rearranged or NPM1-mutated acute leukaemia."@en ;
  schema:url <https://onco.cc/key-papers/paper-augment-101-revumenib-menin-nature-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/?term=AUGMENT-101%20revumenib%20menin%20inhibitor%20KMT2A%20NPM1%20Issa%20Nature%202023>, <https://clinicaltrials.gov/study/NCT04065399> ;
  schema:sameAs <https://doi.org/10.1038/s41586-023-05812-3> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Issa GC, Aldoss I, DiPersio J, et al." ;
  onco:related <https://onco.cc/pairings/menin-plus-venetoclax-hma/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:targets <https://onco.cc/targets/menin/>, <https://onco.cc/targets/kmt2a/>, <https://onco.cc/targets/npm1/> ;
  onco:drugs <https://onco.cc/drugs/revumenib/>, <https://onco.cc/drugs/ziftomenib/> ;
  onco:companies <https://onco.cc/companies/syndax/>, <https://onco.cc/companies/kura-oncology/> ;
  onco:institutions <https://onco.cc/institutions/md-anderson/> ;
  onco:terms <https://onco.cc/terms/mrd-negative-cr/>, <https://onco.cc/terms/orr/> ;
  onco:trials <https://onco.cc/trials/augment-101/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-undruggable-targets/>, <https://onco.cc/bottlenecks/b-resistance/> ;
  onco:journals <https://onco.cc/journals/nature/> .