# OnCo record paper-auperin-prophylactic-cranial-irradiation-sclc-nejm-1999 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-auperin-prophylactic-cranial-irradiation-sclc-nejm-1999/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-auperin-prophylactic-cranial-irradiation-sclc-nejm-1999" ;
  schema:name "Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission"@en ;
  schema:description "Pooling 987 patients from seven trials showed that irradiating the brain of people whose small-cell lung cancer had gone into remission, before any brain secondaries appeared, made them live longer."@en ;
  schema:url <https://onco.cc/key-papers/paper-auperin-prophylactic-cranial-irradiation-sclc-nejm-1999/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJM199908123410703>, <https://pubmed.ncbi.nlm.nih.gov/10441603/> ;
  onco:tag "lung-evidence" ;
  schema:sameAs <https://doi.org/10.1056/NEJM199908123410703> ;
  schema:datePublished "1999"^^xsd:gYear ;
  schema:author "Aupérin A, Arriagada R, Pignon JP, et al." ;
  onco:related <https://onco.cc/key-papers/paper-slotman-n-engl-j-med/>, <https://onco.cc/key-papers/paper-turrisi-twice-daily-thoracic-radiotherapy-limited-sclc-nejm-1999/>, <https://onco.cc/ideas/idea-bio2-brain-met-prevention-trials/> ;
  onco:cancers <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/sclc/>, <https://onco.cc/cancers/limited-stage-sclc/>, <https://onco.cc/cancers/extensive-stage-sclc/> ;
  onco:sections <https://onco.cc/fronts/radiation/> ;
  onco:technologies <https://onco.cc/terms/radiotherapy/>, <https://onco.cc/terms/stereotactic-radiosurgery/> ;
  onco:terms <https://onco.cc/terms/brain-metastases/>, <https://onco.cc/technologies/prophylactic-cranial-irradiation/>, <https://onco.cc/terms/mrd/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-dormancy-mrd/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:journals <https://onco.cc/journals/nejm/> .