# OnCo record paper-baca-punctuated-evolution-chromoplexy-cell-2013 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-baca-punctuated-evolution-chromoplexy-cell-2013/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-baca-punctuated-evolution-chromoplexy-cell-2013" ;
  schema:name "Punctuated evolution of prostate cancer genomes"@en ;
  schema:alternateName "Baca 2013"@en, "chromoplexy"@en, "chromoplexy prostate cancer"@en ;
  schema:description "Cancer is usually described as accumulating damage one change at a time. Sequencing 57 whole prostate cancer genomes showed something else: chains of translocations and deletions that happen together in one burst, disrupting several cancer genes at once."@en ;
  schema:url <https://onco.cc/key-papers/paper-baca-punctuated-evolution-chromoplexy-cell-2013/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.cell.2013.03.021>, <https://pubmed.ncbi.nlm.nih.gov/23622249/> ;
  onco:tag "prostate-evidence" ;
  schema:sameAs <https://doi.org/10.1016/j.cell.2013.03.021> ;
  schema:datePublished "2013"^^xsd:gYear ;
  schema:author "Baca SC, Prandi D, Lawrence MS, et al." ;
  onco:related <https://onco.cc/key-papers/paper-grasso-mutational-landscape-lethal-crpc-nature-2012/>, <https://onco.cc/key-papers/paper-gundem-evolutionary-history-lethal-metastatic-prostate-nature-2015/>, <https://onco.cc/roadmaps/prostate-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-high-risk/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:targets <https://onco.cc/targets/erg/>, <https://onco.cc/targets/tmprss2/> ;
  onco:institutions <https://onco.cc/institutions/broad-institute/>, <https://onco.cc/institutions/weill-cornell-meyer-cancer-center/> ;
  onco:terms <https://onco.cc/terms/ngs/>, <https://onco.cc/terms/chromoplexy/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-tumor-heterogeneity/>, <https://onco.cc/bottlenecks/b-undruggable-targets/> ;
  onco:journals <https://onco.cc/journals/cell/> .