# OnCo record paper-bareche-tnbc-multiomic-heterogeneity-ann-oncol-2018 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-bareche-tnbc-multiomic-heterogeneity-ann-oncol-2018/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-bareche-tnbc-multiomic-heterogeneity-ann-oncol-2018" ;
  schema:name "Unravelling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis"@en ;
  schema:description "Applying the Lehmann subtypes to 550 triple-negative tumours from the two biggest breast cancer genome projects showed each subtype has its own mutations: BL1 is TP53-mutant and unstable, LAR carries PIK3CA in more than half, the immunomodulatory type does best and LAR worst."@en ;
  schema:url <https://onco.cc/key-papers/paper-bareche-tnbc-multiomic-heterogeneity-ann-oncol-2018/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1093/annonc/mdy024>, <https://pubmed.ncbi.nlm.nih.gov/29365031/>, <https://www.cbioportal.org/study/summary?id=brca_metabric>, <https://www.cbioportal.org/study/summary?id=brca_tcga_pub> ;
  schema:sameAs <https://doi.org/10.1093/annonc/mdy024> ;
  schema:datePublished "2018"^^xsd:gYear ;
  schema:author "Bareche Y, Venet D, Ignatiadis M, et al." ;
  onco:cancers <https://onco.cc/cancers/tnbc/> ;
  onco:targets <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/akt/>, <https://onco.cc/targets/pten/>, <https://onco.cc/targets/rb1/>, <https://onco.cc/targets/androgen-receptor/>, <https://onco.cc/targets/kmt2c/>, <https://onco.cc/targets/nf1/> ;
  onco:institutions <https://onco.cc/institutions/institut-jules-bordet/> ;
  onco:pathways <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:terms <https://onco.cc/terms/pam50/> ;
  onco:people <https://onco.cc/people/martine-piccart/> ;
  onco:journals <https://onco.cc/journals/annals-of-oncology/> .