# OnCo record paper-barroso-sousa-breast-tmb-prevalence-ann-oncol-2020 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-barroso-sousa-breast-tmb-prevalence-ann-oncol-2020/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-barroso-sousa-breast-tmb-prevalence-ann-oncol-2020" ;
  schema:name "Prevalence and mutational determinants of high tumor mutation burden in breast cancer"@en ;
  schema:description "Across nearly 4,000 breast cancers, one in twenty carried ten or more mutations per megabase, more often in triple-negative and metastatic tumours, and mostly because of APOBEC enzyme activity or mismatch repair failure."@en ;
  schema:url <https://onco.cc/key-papers/paper-barroso-sousa-breast-tmb-prevalence-ann-oncol-2020/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.annonc.2019.11.010>, <https://pubmed.ncbi.nlm.nih.gov/32067680/> ;
  schema:sameAs <https://doi.org/10.1016/j.annonc.2019.11.010> ;
  schema:datePublished "2020"^^xsd:gYear ;
  schema:author "Barroso-Sousa R, Jain E, Cohen O, et al." ;
  onco:related <https://onco.cc/biomarkers/tmb-high/> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:technologies <https://onco.cc/technologies/tmb-testing/> ;
  onco:institutions <https://onco.cc/institutions/dana-farber/> ;
  onco:terms <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/mutational-signature/> ;
  onco:people <https://onco.cc/people/nancy-lin/>, <https://onco.cc/people/sara-tolaney/>, <https://onco.cc/people/eric-winer/> ;
  onco:journals <https://onco.cc/journals/annals-of-oncology/> .