# OnCo record paper-beer-prevail-enzalutamide-nejm-2014 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-beer-prevail-enzalutamide-nejm-2014/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-beer-prevail-enzalutamide-nejm-2014" ;
  schema:name "PREVAIL: enzalutamide in metastatic prostate cancer before chemotherapy"@en ;
  schema:alternateName "PREVAIL"@en, "Beer 2014 enzalutamide chemotherapy-naive"@en ;
  schema:description "The same drug given before chemotherapy rather than after it. At one year, 65 percent of men on enzalutamide had no sign of the cancer growing on scans, against 14 percent on placebo, and the need for chemotherapy was pushed a long way back."@en ;
  schema:url <https://onco.cc/key-papers/paper-beer-prevail-enzalutamide-nejm-2014/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/nejmoa1405095>, <https://pubmed.ncbi.nlm.nih.gov/24881730/>, <https://clinicaltrials.gov/study/NCT01212991> ;
  onco:tag "prostate-evidence" ;
  schema:sameAs <https://doi.org/10.1056/nejmoa1405095> ;
  schema:datePublished "2014"^^xsd:gYear ;
  schema:author "Beer TM, Armstrong AJ, Rathkopf DE, et al." ;
  onco:related <https://onco.cc/key-papers/paper-scher-affirm-enzalutamide-nejm-2012/>, <https://onco.cc/key-papers/paper-abiraterone-acetate-prostate-n-engl-j-med-2013/>, <https://onco.cc/roadmaps/prostate-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:sections <https://onco.cc/fronts/hormonal/>, <https://onco.cc/fronts/targeted-therapy/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/> ;
  onco:drugs <https://onco.cc/drugs/enzalutamide/> ;
  onco:companies <https://onco.cc/companies/astellas/>, <https://onco.cc/companies/pfizer/> ;
  onco:terms <https://onco.cc/terms/castration-resistance/>, <https://onco.cc/terms/psa/>, <https://onco.cc/terms/radiographic-progression-free-survival/>, <https://onco.cc/terms/metastasis-free-survival/> ;
  onco:people <https://onco.cc/people/johann-de-bono/>, <https://onco.cc/people/karim-fizazi/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-resistance/>, <https://onco.cc/bottlenecks/b-combination-space/> ;
  onco:journals <https://onco.cc/journals/nejm/> .