# OnCo record paper-cartitude-4-cilta-cel-nejm-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-cartitude-4-cilta-cel-nejm-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-cartitude-4-cilta-cel-nejm-2023" ;
  schema:name "CARTITUDE-4: cilta-cel CAR-T versus standard combinations after one to three prior lines of myeloma therapy"@en ;
  schema:description "Moving BCMA CAR-T to the second line cut the risk of progression or death by 74% compared with standard triplets, and later improved overall survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-cartitude-4-cilta-cel-nejm-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2303379>, <https://clinicaltrials.gov/study/NCT04181827> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2303379> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "San-Miguel J, Dhakal B, Yong K, et al." ;
  onco:related <https://onco.cc/key-papers/paper-karmma-3-ide-cel-nejm-2023/> ;
  onco:cancers <https://onco.cc/cancers/multiple-myeloma/> ;
  onco:technologies <https://onco.cc/technologies/car-t/> ;
  onco:targets <https://onco.cc/targets/bcma/> ;
  onco:drugs <https://onco.cc/drugs/ciltacabtagene-autoleucel/>, <https://onco.cc/drugs/daratumumab/>, <https://onco.cc/drugs/pomalidomide/>, <https://onco.cc/drugs/bortezomib/> ;
  onco:companies <https://onco.cc/companies/legend-biotech/>, <https://onco.cc/companies/johnson-johnson/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/os/>, <https://onco.cc/terms/mrd-negativity-myeloma/>, <https://onco.cc/terms/crs/> ;
  onco:trials <https://onco.cc/trials/cartitude-4/>, <https://onco.cc/trials/cartitude-5/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/>, <https://onco.cc/bottlenecks/b-global-access/> ;
  onco:journals <https://onco.cc/journals/nejm/> .