# OnCo record paper-challenge-exercise-nejm-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-challenge-exercise-nejm-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-challenge-exercise-nejm-2025" ;
  schema:name "CHALLENGE: a structured exercise programme after chemotherapy improves survival in colon cancer"@en ;
  schema:description "In CHALLENGE, three years of supervised, goal-based exercise after adjuvant chemotherapy for colon cancer reduced recurrence or death by 28% and deaths by 37%, the first randomised proof that exercise itself improves cancer survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-challenge-exercise-nejm-2025/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2502760>, <https://clinicaltrials.gov/study/NCT00819208>, <https://pubmed.ncbi.nlm.nih.gov/40450658/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2502760> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Courneya KS, Vardy JL, O'Callaghan CJ, et al. (Canadian Cancer Trials Group CO.21)" ;
  onco:related <https://onco.cc/ideas/idea-exercise-as-adjuvant/>, <https://onco.cc/ideas/idea-bio2-exercise-reimbursement/>, <https://onco.cc/ideas/idea-bio2-gdf15-plus-exercise/>, <https://onco.cc/roadmaps/survivorship-roadmap/>, <https://onco.cc/key-papers/paper-idea-duration-adjuvant-stage-iii-colon-nejm-2018/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/colon-cancer/> ;
  onco:sections <https://onco.cc/fronts/nutrition-lifestyle/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/exercise-oncology/> ;
  onco:companies <https://onco.cc/companies/cctg/> ;
  onco:people <https://onco.cc/people/dancey-janet/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-survivorship/>, <https://onco.cc/bottlenecks/b-prevention-adoption/>, <https://onco.cc/bottlenecks/b-generic-repurposing/>, <https://onco.cc/bottlenecks/b-funding-allocation/> ;
  onco:journals <https://onco.cc/journals/nejm/> .