# OnCo record paper-chan-seng-yue-pancreatic-transcription-phenotypes-nat-genet-2020 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-chan-seng-yue-pancreatic-transcription-phenotypes-nat-genet-2020/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-chan-seng-yue-pancreatic-transcription-phenotypes-nat-genet-2020" ;
  schema:name "Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution"@en ;
  schema:description "Whole genomes and transcriptomes from purified tumour cells showed that the classical and basal-like types are not two boxes but a continuum of mixed cell populations, set by how many copies of mutant KRAS and GATA6 a tumour has gained, often after its genome doubled."@en ;
  schema:url <https://onco.cc/key-papers/paper-chan-seng-yue-pancreatic-transcription-phenotypes-nat-genet-2020/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41588-019-0566-9>, <https://pubmed.ncbi.nlm.nih.gov/31932696/> ;
  schema:sameAs <https://doi.org/10.1038/s41588-019-0566-9> ;
  schema:datePublished "2020"^^xsd:gYear ;
  schema:author "Chan-Seng-Yue M, Kim JC, Wilson GW, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/rna-seq/>, <https://onco.cc/technologies/single-cell-spatial/> ;
  onco:targets <https://onco.cc/targets/kras/> ;
  onco:institutions <https://onco.cc/institutions/oicr/>, <https://onco.cc/institutions/princess-margaret/>, <https://onco.cc/institutions/cold-spring-harbor/> ;
  onco:pathways <https://onco.cc/pathways/chromosomal-instability/>, <https://onco.cc/pathways/clonal-evolution/> ;
  onco:terms <https://onco.cc/terms/whole-genome-doubling/>, <https://onco.cc/terms/copy-number-variation-term/> ;
  onco:people <https://onco.cc/people/david-tuveson/> ;
  onco:journals <https://onco.cc/journals/nature-genetics/> .