# OnCo record paper-chapman-vemurafenib-nejm-2011 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-chapman-vemurafenib-nejm-2011/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-chapman-vemurafenib-nejm-2011" ;
  schema:name "BRIM-3: improved survival with vemurafenib in melanoma with BRAF V600E mutation"@en ;
  schema:description "Vemurafenib, the first drug targeting the BRAF V600E mutation, reduced deaths by 63 percent compared with dacarbazine chemotherapy in metastatic melanoma, launching targeted therapy in the disease."@en ;
  schema:url <https://onco.cc/key-papers/paper-chapman-vemurafenib-nejm-2011/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1103782>, <https://pubmed.ncbi.nlm.nih.gov/21639808/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa1103782> ;
  schema:datePublished "2011"^^xsd:gYear ;
  schema:author "Chapman PB, Hauschild A, Robert C, et al." ;
  onco:cancers <https://onco.cc/cancers/braf-v600-melanoma/> ;
  onco:drugs <https://onco.cc/drugs/vemurafenib/> ;
  onco:journals <https://onco.cc/journals/nejm/> .