# OnCo record paper-codebreak-100-sotorasib-kras-g12c-pancreatic-nejm-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-codebreak-100-sotorasib-kras-g12c-pancreatic-nejm-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-codebreak-100-sotorasib-kras-g12c-pancreatic-nejm-2023" ;
  schema:name "CodeBreaK 100: sotorasib in KRAS p.G12C-mutated advanced pancreatic cancer"@en ;
  schema:description "The first KRAS-blocking pill shrank tumours in about one in five patients with heavily pretreated pancreatic cancer carrying the G12C mutation and controlled the disease in most for a few months. Modest as that is, it was the first direct hit on the gene that drives nearly every pancreatic cancer."@en ;
  schema:url <https://onco.cc/key-papers/paper-codebreak-100-sotorasib-kras-g12c-pancreatic-nejm-2023/> ;
  schema:dateModified "2026-09-21"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2208470>, <https://pubmed.ncbi.nlm.nih.gov/36546651/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2208470> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Strickler JH, Satake H, George TJ, et al." ;
  onco:cancers <https://onco.cc/cancers/kras-g12c-pdac/>, <https://onco.cc/cancers/pancreatic/> ;
  onco:drugs <https://onco.cc/drugs/sotorasib/> ;
  onco:journals <https://onco.cc/journals/nejm/> .