# OnCo record paper-conti-trans-ancestry-gwas-prostate-nat-genet-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-conti-trans-ancestry-gwas-prostate-nat-genet-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-conti-trans-ancestry-gwas-prostate-nat-genet-2021" ;
  schema:name "Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction"@en ;
  schema:alternateName "Conti 2021"@en, "prostate polygenic risk score 269 variants"@en, "trans-ancestry prostate GWAS"@en ;
  schema:description "The largest genetic study of prostate cancer pooled 107,247 men with the disease and 127,006 without, across ancestries. It brought the number of known risk variants to 269 and showed that men of African ancestry carry, on average, more than twice the genetic risk score of men of European ancestry."@en ;
  schema:url <https://onco.cc/key-papers/paper-conti-trans-ancestry-gwas-prostate-nat-genet-2021/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41588-020-00748-0>, <https://pubmed.ncbi.nlm.nih.gov/33398198/> ;
  onco:tag "prostate-evidence" ;
  schema:sameAs <https://doi.org/10.1038/s41588-020-00748-0> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Conti DV, Darst BF, Moss LC, et al." ;
  onco:related <https://onco.cc/key-papers/paper-dess-black-race-prostate-mortality-jama-oncol-2019/>, <https://onco.cc/key-papers/paper-pritchard-inherited-dna-repair-metastatic-prostate-nejm-2016/>, <https://onco.cc/ideas/idea-prev-prs-screening-start-age/>, <https://onco.cc/ideas/idea-prev-mri-first-prostate-screening-prs/>, <https://onco.cc/roadmaps/prostate-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/prostate/> ;
  onco:sections <https://onco.cc/fronts/prevention/>, <https://onco.cc/fronts/early-detection/>, <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/> ;
  onco:terms <https://onco.cc/terms/screening/>, <https://onco.cc/terms/polygenic-risk-score/>, <https://onco.cc/terms/other-cause-mortality/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-hereditary-risk/>, <https://onco.cc/bottlenecks/b-early-detection/>, <https://onco.cc/bottlenecks/b-trial-diversity/>, <https://onco.cc/bottlenecks/b-global-access/> ;
  onco:journals <https://onco.cc/journals/nature-genetics/> .