# OnCo record paper-crane-smad4-progression-pattern-locally-advanced-jco-2011 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-crane-smad4-progression-pattern-locally-advanced-jco-2011/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-crane-smad4-progression-pattern-locally-advanced-jco-2011" ;
  schema:name "Phase II trial of cetuximab, gemcitabine, and oxaliplatin followed by chemoradiation with cetuximab for locally advanced (T4) pancreatic adenocarcinoma: correlation of Smad4(Dpc4) immunostaining with pattern of disease progression"@en ;
  schema:description "In 69 people with locally advanced pancreatic cancer, an ordinary Smad4 stain on the diagnostic needle sample predicted whether the cancer would grow locally or spread, the finding that supports using it to decide who gets radiotherapy."@en ;
  schema:url <https://onco.cc/key-papers/paper-crane-smad4-progression-pattern-locally-advanced-jco-2011/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2010.33.8038>, <https://pubmed.ncbi.nlm.nih.gov/21709185/> ;
  schema:sameAs <https://doi.org/10.1200/JCO.2010.33.8038> ;
  schema:datePublished "2011"^^xsd:gYear ;
  schema:author "Crane CH, Varadhachary GR, Yordy JS, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/locally-advanced-pdac/> ;
  onco:targets <https://onco.cc/targets/smad4/> ;
  onco:drugs <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/drugs/cetuximab/> ;
  onco:institutions <https://onco.cc/institutions/md-anderson/> ;
  onco:terms <https://onco.cc/terms/ihc/> ;
  onco:journals <https://onco.cc/journals/jco/> .