# OnCo record paper-ct041-st-01-lancet-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-ct041-st-01-lancet-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-ct041-st-01-lancet-2025" ;
  schema:name "Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial"@en ;
  schema:description "The first randomised trial of CAR-T cells in a solid tumour: in heavily pretreated Claudin 18.2-positive stomach cancer, satri-cel held the disease for a median of 3.25 months against 1.77 months on the doctor's choice of drug, with almost universal cytokine release syndrome."@en ;
  schema:url <https://onco.cc/key-papers/paper-ct041-st-01-lancet-2025/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S0140-6736(25)00860-8>, <https://pubmed.ncbi.nlm.nih.gov/40460847/>, <https://clinicaltrials.gov/study/NCT04581473> ;
  onco:tag "china" ;
  schema:sameAs <https://doi.org/10.1016/S0140-6736(25)00860-8> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Qi C, Liu C, Peng Z, et al." ;
  onco:cancers <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/gastric-cldn18-2-positive/> ;
  onco:technologies <https://onco.cc/technologies/car-t/> ;
  onco:targets <https://onco.cc/targets/cldn18-2/> ;
  onco:drugs <https://onco.cc/drugs/satricabtagene-autoleucel/> ;
  onco:companies <https://onco.cc/companies/carsgen/> ;
  onco:institutions <https://onco.cc/institutions/pku-cancer-hospital/> ;
  onco:trials <https://onco.cc/trials/nct04581473/> ;
  onco:people <https://onco.cc/people/qi-changsong/>, <https://onco.cc/people/shen-lin/> ;
  onco:journals <https://onco.cc/journals/lancet/> .