# OnCo record paper-darnell-jak-stat-science-1994 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-darnell-jak-stat-science-1994/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-darnell-jak-stat-science-1994" ;
  schema:name "Darnell, Kerr and Stark 1994: JAK-STAT pathways and transcriptional activation by interferons"@en ;
  schema:description "The review that defined the JAK-STAT pathway, the direct route by which interferons and many other cytokines tell a cell's genes to respond, and which is now the target of JAK inhibitors used in blood cancers."@en ;
  schema:url <https://onco.cc/key-papers/paper-darnell-jak-stat-science-1994/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.8197455> ;
  schema:sameAs <https://doi.org/10.1126/science.8197455> ;
  schema:datePublished "1994"^^xsd:gYear ;
  schema:author "Darnell JE Jr, Kerr IM, Stark GR." ;
  onco:related <https://onco.cc/key-papers/paper-grivennikov-immunity-inflammation-cancer-cell-2010/> ;
  onco:targets <https://onco.cc/targets/jak2/>, <https://onco.cc/targets/ifnar1/> ;
  onco:pathways <https://onco.cc/pathways/jak-stat/> ;
  onco:terms <https://onco.cc/terms/cytokine/>, <https://onco.cc/terms/signalling-pathway/> .