# OnCo record paper-echo-acalabrutinib-bendamustine-rituximab-mantle-cell-jco-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-echo-acalabrutinib-bendamustine-rituximab-mantle-cell-jco-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-echo-acalabrutinib-bendamustine-rituximab-mantle-cell-jco-2025" ;
  schema:name "Acalabrutinib plus bendamustine-rituximab in untreated mantle cell lymphoma"@en ;
  schema:alternateName "ECHO"@en, "Wang 2025"@en, "Acalabrutinib with bendamustine and rituximab"@en ;
  schema:description "Repeating the SHINE design with a more selective targeted tablet gave another seventeen months before relapse, and again did not extend life."@en ;
  schema:url <https://onco.cc/key-papers/paper-echo-acalabrutinib-bendamustine-rituximab-mantle-cell-jco-2025/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO-25-00690>, <https://pubmed.ncbi.nlm.nih.gov/40311141/>, <https://europepmc.org/article/MED/40311141> ;
  onco:tag "lymphoma-evidence" ;
  schema:sameAs <https://doi.org/10.1200/JCO-25-00690> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Wang M, Salek D, Belada D, et al." ;
  onco:related <https://onco.cc/roadmaps/lymphoma-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/mantle-cell-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/>, <https://onco.cc/fronts/chemotherapy/> ;
  onco:targets <https://onco.cc/targets/btk/>, <https://onco.cc/targets/cd20/>, <https://onco.cc/targets/ccnd1/> ;
  onco:drugs <https://onco.cc/drugs/acalabrutinib/>, <https://onco.cc/drugs/bendamustine/>, <https://onco.cc/drugs/rituximab/> ;
  onco:companies <https://onco.cc/companies/astrazeneca/> ;
  onco:pathways <https://onco.cc/pathways/bcr-signalling/> ;
  onco:trials <https://onco.cc/trials/nct02972840/>, <https://onco.cc/trials/shine/>, <https://onco.cc/trials/enrich/> ;
  onco:people <https://onco.cc/people/michael-wang/>, <https://onco.cc/people/martin-dreyling/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-aging-comorbidity/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:journals <https://onco.cc/journals/jco/> .