# OnCo record paper-eliana-tisagenlecleucel-nejm-2018 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-eliana-tisagenlecleucel-nejm-2018/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-eliana-tisagenlecleucel-nejm-2018" ;
  schema:name "ELIANA: the global trial that made tisagenlecleucel the first approved CAR-T therapy for children and young adults with relapsed ALL"@en ;
  schema:description "Across 25 centres, 81% of children and young adults with relapsed or refractory ALL went into remission after a single tisagenlecleucel infusion, and half were still event-free a year later."@en ;
  schema:url <https://onco.cc/key-papers/paper-eliana-tisagenlecleucel-nejm-2018/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1709866>, <https://clinicaltrials.gov/study/NCT02435849> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa1709866> ;
  schema:datePublished "2018"^^xsd:gYear ;
  schema:author "Maude SL, Laetsch TW, Buechner J, et al." ;
  onco:related <https://onco.cc/key-papers/paper-maude-ctl019-all-nejm-2014/>, <https://onco.cc/technologies/apheresis-starting-material/> ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/all-paediatric-relapsed/> ;
  onco:technologies <https://onco.cc/technologies/car-t/> ;
  onco:targets <https://onco.cc/targets/cd19/> ;
  onco:drugs <https://onco.cc/drugs/tisagenlecleucel/>, <https://onco.cc/drugs/obecabtagene-autoleucel/> ;
  onco:companies <https://onco.cc/companies/novartis/> ;
  onco:institutions <https://onco.cc/institutions/penn-abramson/> ;
  onco:terms <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/>, <https://onco.cc/terms/efs/> ;
  onco:trials <https://onco.cc/trials/eliana/> ;
  onco:people <https://onco.cc/people/carl-june/>, <https://onco.cc/people/bruce-levine/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/>, <https://onco.cc/bottlenecks/b-drug-pricing/>, <https://onco.cc/bottlenecks/b-global-access/> ;
  onco:journals <https://onco.cc/journals/nejm/> .