# OnCo record paper-ev-302-nejm-2024 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-ev-302-nejm-2024/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-ev-302-nejm-2024" ;
  schema:name "EV-302: enfortumab vedotin plus pembrolizumab replaces chemotherapy as first treatment for advanced bladder cancer"@en ;
  schema:description "Combining the Nectin-4 antibody-drug conjugate enfortumab vedotin with pembrolizumab nearly doubled survival compared with platinum chemotherapy in advanced urothelial cancer, the biggest advance in this disease in 40 years."@en ;
  schema:url <https://onco.cc/key-papers/paper-ev-302-nejm-2024/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2312117>, <https://clinicaltrials.gov/study/NCT04223856> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2312117> ;
  schema:datePublished "2024"^^xsd:gYear ;
  schema:author "Powles T, Valderrama BP, Gupta S, et al." ;
  onco:cancers <https://onco.cc/cancers/urothelial/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/nectin4/>, <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/enfortumab-vedotin/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:companies <https://onco.cc/companies/astellas/>, <https://onco.cc/companies/pfizer/>, <https://onco.cc/companies/merck/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/os/>, <https://onco.cc/terms/orr/>, <https://onco.cc/terms/first-line/>, <https://onco.cc/terms/standard-of-care/>, <https://onco.cc/terms/payload/> ;
  onco:trials <https://onco.cc/trials/ev-302/> ;
  onco:people <https://onco.cc/people/shilpa-gupta/>, <https://onco.cc/people/shin-sang-joon/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-combination-space/>, <https://onco.cc/bottlenecks/b-drug-pricing/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:journals <https://onco.cc/journals/nejm/> .