# OnCo record paper-explorer-avapritinib-advanced-systemic-mastocytosis-nat-med-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-explorer-avapritinib-advanced-systemic-mastocytosis-nat-med-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-explorer-avapritinib-advanced-systemic-mastocytosis-nat-med-2021" ;
  schema:name "EXPLORER: safety and efficacy of avapritinib in advanced systemic mastocytosis (phase 1)"@en ;
  schema:description "The first study of avapritinib, a drug designed to hit the KIT D816V mutation that drives most mastocytosis, produced responses in three quarters of patients with advanced disease and set the dose for later trials."@en ;
  schema:url <https://onco.cc/key-papers/paper-explorer-avapritinib-advanced-systemic-mastocytosis-nat-med-2021/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-021-01538-9>, <https://pubmed.ncbi.nlm.nih.gov/34873347/> ;
  schema:sameAs <https://doi.org/10.1038/s41591-021-01538-9> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "DeAngelo DJ, Radia DH, George TI, et al." ;
  onco:cancers <https://onco.cc/cancers/advanced-systemic-mastocytosis/> ;
  onco:drugs <https://onco.cc/drugs/avapritinib/> ;
  onco:journals <https://onco.cc/journals/nature-medicine/> .