# OnCo record paper-extreme-vermorken-nejm-2008 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-extreme-vermorken-nejm-2008/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-extreme-vermorken-nejm-2008" ;
  schema:name "EXTREME: platinum-based chemotherapy plus cetuximab in recurrent or metastatic head and neck cancer"@en ;
  schema:description "Adding cetuximab to platinum and fluorouracil lengthened survival in recurrent or metastatic head and neck cancer from 7.4 to 10.1 months, the first improvement in first-line treatment in decades."@en ;
  schema:url <https://onco.cc/key-papers/paper-extreme-vermorken-nejm-2008/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa0802656>, <https://pubmed.ncbi.nlm.nih.gov/18784101/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa0802656> ;
  schema:datePublished "2008"^^xsd:gYear ;
  schema:author "Vermorken JB, Mesia R, Rivera F, et al." ;
  onco:cancers <https://onco.cc/cancers/recurrent-metastatic-hnscc/> ;
  onco:drugs <https://onco.cc/drugs/cetuximab/> ;
  onco:trials <https://onco.cc/trials/extreme/> ;
  onco:journals <https://onco.cc/journals/nejm/> .