# OnCo record paper-flame-focal-boost-prostate-jco-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-flame-focal-boost-prostate-jco-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-flame-focal-boost-prostate-jco-2021" ;
  schema:name "Focal boost to the intraprostatic tumor in external beam radiotherapy for patients with localized prostate cancer: results from the FLAME randomized phase III trial"@en ;
  schema:description "A trial of 571 men with intermediate or high-risk prostate cancer gave half of them an extra dose, up to 95 Gy, to the tumour visible on MRI inside the prostate. After five years 92 per cent of the boosted group were free of PSA relapse against 85 per cent, with no measurable increase in side effects and no difference in survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-flame-focal-boost-prostate-jco-2021/> ;
  schema:dateModified "2026-10-20"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.20.02873>, <https://pubmed.ncbi.nlm.nih.gov/33471548/> ;
  onco:tag "precision", "radiation" ;
  schema:sameAs <https://doi.org/10.1200/JCO.20.02873> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Kerkmeijer LGW, Groen VH, Pos FJ, et al." ;
  onco:cancers <https://onco.cc/cancers/prostate/> ;
  onco:sections <https://onco.cc/fronts/radiation/> ;
  onco:technologies <https://onco.cc/technologies/dose-painting/>, <https://onco.cc/technologies/imrt-igrt/> ;
  onco:terms <https://onco.cc/terms/target-delineation-variability/>, <https://onco.cc/terms/organs-at-risk/> ;
  onco:journals <https://onco.cc/journals/jco/> .