# OnCo record paper-galaxy-signatera-nat-med-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-galaxy-signatera-nat-med-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-galaxy-signatera-nat-med-2023" ;
  schema:name "GALAXY: tumour DNA in blood four weeks after bowel cancer surgery predicts relapse tenfold"@en ;
  schema:description "In 1,039 Japanese patients with resected colorectal cancer, a positive Signatera test at week 4 carried a tenfold higher recurrence risk, and only ctDNA-positive patients appeared to benefit from adjuvant chemotherapy."@en ;
  schema:url <https://onco.cc/key-papers/paper-galaxy-signatera-nat-med-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-022-02115-4>, <https://pubmed.ncbi.nlm.nih.gov/36646802/>, <https://europepmc.org/article/MED/36646802> ;
  schema:sameAs <https://doi.org/10.1038/s41591-022-02115-4> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Kotani D, Oki E, Nakamura Y, et al." ;
  onco:related <https://onco.cc/key-papers/paper-dynamic-nejm-2022/>, <https://onco.cc/ideas/idea-ctdna-guided-adjuvant-crc/>, <https://onco.cc/ideas/idea-tr2-ctdna-mrd-qualification/>, <https://onco.cc/biomarkers/ctdna-mrd-positive/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/colon-cancer/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/continuous-ctdna-monitoring/>, <https://onco.cc/drugs/signatera/> ;
  onco:drugs <https://onco.cc/drugs/signatera/> ;
  onco:companies <https://onco.cc/companies/natera/> ;
  onco:institutions <https://onco.cc/institutions/ncc-japan/> ;
  onco:terms <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/vaf/>, <https://onco.cc/terms/tumour-informed-assay/> ;
  onco:trials <https://onco.cc/trials/circulate-japan/> ;
  onco:people <https://onco.cc/people/yoshino-takayuki/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dormancy-mrd/>, <https://onco.cc/bottlenecks/b-biomarker-validation/>, <https://onco.cc/bottlenecks/b-real-world-evidence/> ;
  onco:journals <https://onco.cc/journals/nature-medicine/> .