# OnCo record paper-garcia-aguilar-opra-organ-preservation-jco-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-garcia-aguilar-opra-organ-preservation-jco-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-garcia-aguilar-opra-organ-preservation-jco-2022" ;
  schema:name "Organ preservation in patients with rectal adenocarcinoma treated with total neoadjuvant therapy (OPRA)"@en ;
  schema:description "Planning for watch and wait from the start, rather than stumbling into it, let half of 324 rectal cancer patients keep their rectum with no loss of disease-free survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-garcia-aguilar-opra-organ-preservation-jco-2022/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.22.00032>, <https://pubmed.ncbi.nlm.nih.gov/35483010/>, <https://europepmc.org/article/MED/35483010> ;
  onco:tag "colorectal-evidence" ;
  schema:sameAs <https://doi.org/10.1200/JCO.22.00032> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Garcia-Aguilar J, Patil S, Gollub MJ, et al." ;
  onco:related <https://onco.cc/key-papers/paper-habr-gama-nonoperative-stage-0-rectal-ann-surg-2004/>, <https://onco.cc/key-papers/paper-bahadoer-rapido-short-course-radiotherapy-lancet-oncol-2021/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/rectal-cancer/> ;
  onco:sections <https://onco.cc/fronts/surgery/>, <https://onco.cc/fronts/radiation/> ;
  onco:technologies <https://onco.cc/terms/radiotherapy/>, <https://onco.cc/technologies/mri/> ;
  onco:drugs <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/drugs/fluorouracil/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:terms <https://onco.cc/terms/organ-preservation/>, <https://onco.cc/terms/clinical-complete-response/>, <https://onco.cc/terms/total-neoadjuvant-therapy/>, <https://onco.cc/terms/total-mesorectal-excision/> ;
  onco:trials <https://onco.cc/trials/opra/> ;
  onco:people <https://onco.cc/people/julio-garcia-aguilar/>, <https://onco.cc/people/andrea-cercek/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-surgery-radiation-innovation/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:journals <https://onco.cc/journals/jco/> .