# OnCo record paper-giraldo-gallbladder-msk-impact-ccr-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-giraldo-gallbladder-msk-impact-ccr-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-giraldo-gallbladder-msk-impact-ccr-2022" ;
  schema:name "Comprehensive molecular characterization of gallbladder carcinoma and potential targets for intervention"@en ;
  schema:description "The largest sequencing study of gallbladder cancer at one centre, 244 samples on a 505-gene panel, found TP53 in 63%, HER2 changes in 15% and something actionable in a third of patients; SMAD4 and STK11 marked shorter survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-giraldo-gallbladder-msk-impact-ccr-2022/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/1078-0432.ccr-22-1954>, <https://pubmed.ncbi.nlm.nih.gov/36228155/>, <https://www.cbioportal.org/study/summary?id=gbc_mskcc_2022> ;
  schema:sameAs <https://doi.org/10.1158/1078-0432.ccr-22-1954> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Giraldo NA, Drill E, Satravada BA, et al." ;
  onco:cancers <https://onco.cc/cancers/gallbladder/> ;
  onco:targets <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/cdkn2a/>, <https://onco.cc/targets/her2/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/smad4/>, <https://onco.cc/targets/stk11/>, <https://onco.cc/targets/ntrk/>, <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/brca/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:people <https://onco.cc/people/ghassan-abou-alfa/> ;
  onco:journals <https://onco.cc/journals/clinical-cancer-research/> .