# OnCo record paper-hargrave-dabrafenib-trametinib-paediatric-hgg-jco-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-hargrave-dabrafenib-trametinib-paediatric-hgg-jco-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-hargrave-dabrafenib-trametinib-paediatric-hgg-jco-2023" ;
  schema:name "Dabrafenib plus trametinib in relapsed or refractory BRAF V600-mutant paediatric high-grade glioma"@en ;
  schema:description "In children whose BRAF V600-mutant high-grade glioma had relapsed, the combination of dabrafenib and trametinib shrank tumours in more than half and gave responses lasting well over a year, far better than historical chemotherapy."@en ;
  schema:url <https://onco.cc/key-papers/paper-hargrave-dabrafenib-trametinib-paediatric-hgg-jco-2023/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.23.00558>, <https://pubmed.ncbi.nlm.nih.gov/37643378/> ;
  schema:sameAs <https://doi.org/10.1200/JCO.23.00558> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Hargrave DR, Terashima K, Hara J, et al." ;
  onco:cancers <https://onco.cc/cancers/paediatric-high-grade-glioma/> ;
  onco:drugs <https://onco.cc/drugs/dabrafenib/>, <https://onco.cc/drugs/trametinib/> ;
  onco:journals <https://onco.cc/journals/jco/> .