# OnCo record paper-heining-nrg1-fusions-kras-wild-type-pancreatic-cancer-discov-2018 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-heining-nrg1-fusions-kras-wild-type-pancreatic-cancer-discov-2018/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-heining-nrg1-fusions-kras-wild-type-pancreatic-cancer-discov-2018" ;
  schema:name "Heining 2018: NRG1 fusions in KRAS wild-type pancreatic cancer"@en ;
  schema:description "Whole-genome and RNA sequencing of pancreatic cancers in younger patients found that most of the tumours without a KRAS mutation instead carried a fusion of the NRG1 gene, and two patients given a HER-family blocker responded. It established NRG1 fusions as the driver to look for in KRAS wild-type pancreatic cancer."@en ;
  schema:url <https://onco.cc/key-papers/paper-heining-nrg1-fusions-kras-wild-type-pancreatic-cancer-discov-2018/> ;
  schema:dateModified "2026-09-21"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/2159-8290.CD-18-0036>, <https://pubmed.ncbi.nlm.nih.gov/29802158/> ;
  schema:sameAs <https://doi.org/10.1158/2159-8290.CD-18-0036> ;
  schema:datePublished "2018"^^xsd:gYear ;
  schema:author "Heining C, Horak P, Uhrig S, et al." ;
  onco:cancers <https://onco.cc/cancers/kras-wild-type-pdac/>, <https://onco.cc/cancers/pancreatic/> ;
  onco:drugs <https://onco.cc/drugs/afatinib/> ;
  onco:journals <https://onco.cc/journals/cancer-discovery/> .