# OnCo record paper-heinrich-pdgfra-gist-science-2003 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-heinrich-pdgfra-gist-science-2003/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-heinrich-pdgfra-gist-science-2003" ;
  schema:name "PDGFRA activating mutations in gastrointestinal stromal tumours"@en ;
  schema:description "This study found that most gastrointestinal stromal tumours without KIT mutations instead carry activating mutations in the related receptor PDGFRA, including the D842V mutation that resists imatinib, completing the genetic definition of the disease."@en ;
  schema:url <https://onco.cc/key-papers/paper-heinrich-pdgfra-gist-science-2003/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.1079666>, <https://pubmed.ncbi.nlm.nih.gov/12522257/> ;
  schema:sameAs <https://doi.org/10.1126/science.1079666> ;
  schema:datePublished "2003"^^xsd:gYear ;
  schema:author "Heinrich MC, Corless CL, Duensing A, et al." ;
  onco:cancers <https://onco.cc/cancers/gist-pdgfra-d842v/> ;
  onco:journals <https://onco.cc/journals/science/> .