# OnCo record paper-herschkowitz-rb1-loss-basal-like-bcr-2008 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-herschkowitz-rb1-loss-basal-like-bcr-2008/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-herschkowitz-rb1-loss-basal-like-bcr-2008" ;
  schema:name "The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas"@en ;
  schema:description "Loss of one copy of the RB1 gene was found in 72% of basal-like breast cancers, with low RB1 messenger RNA and high p16, and an RB1-loss expression signature predicted outcome and possibly chemotherapy response."@en ;
  schema:url <https://onco.cc/key-papers/paper-herschkowitz-rb1-loss-basal-like-bcr-2008/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1186/bcr2142>, <https://pubmed.ncbi.nlm.nih.gov/18782450/> ;
  schema:sameAs <https://doi.org/10.1186/bcr2142> ;
  schema:datePublished "2008"^^xsd:gYear ;
  schema:author "Herschkowitz JI, He X, Fan C, Perou CM." ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:targets <https://onco.cc/targets/rb1/>, <https://onco.cc/targets/cdk4-6/> ;
  onco:pathways <https://onco.cc/pathways/p53-cell-cycle/> ;
  onco:people <https://onco.cc/people/charles-perou/> ;
  onco:journals <https://onco.cc/journals/breast-cancer-research/> .