# OnCo record paper-hollstein-p53-mutations-science-1991 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-hollstein-p53-mutations-science-1991/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-hollstein-p53-mutations-science-1991" ;
  schema:name "Hollstein 1991: p53 mutations in human cancers"@en ;
  schema:description "The survey that showed p53 is the most commonly altered gene in human cancer and that the pattern of its mutations differs by cancer type and by cause, such as tobacco smoke in lung cancer and a dietary toxin in liver cancer."@en ;
  schema:url <https://onco.cc/key-papers/paper-hollstein-p53-mutations-science-1991/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.1905840> ;
  schema:sameAs <https://doi.org/10.1126/science.1905840> ;
  schema:datePublished "1991"^^xsd:gYear ;
  schema:author "Hollstein M, Sidransky D, Vogelstein B, Harris CC." ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/colorectal/> ;
  onco:targets <https://onco.cc/targets/tp53/> ;
  onco:institutions <https://onco.cc/institutions/johns-hopkins/> ;
  onco:terms <https://onco.cc/terms/tp53-mutated/>, <https://onco.cc/terms/tumour-suppressor-gene/>, <https://onco.cc/terms/mutational-signature/> ;
  onco:people <https://onco.cc/people/bert-vogelstein/> .