# OnCo record paper-hussain-swog-9346-intermittent-androgen-deprivation-nejm-2013 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-hussain-swog-9346-intermittent-androgen-deprivation-nejm-2013/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-hussain-swog-9346-intermittent-androgen-deprivation-nejm-2013" ;
  schema:name "SWOG 9346: intermittent versus continuous androgen deprivation in metastatic prostate cancer"@en ;
  schema:alternateName "SWOG 9346"@en, "S9346"@en, "Hussain 2013 intermittent androgen deprivation"@en ;
  schema:description "Hormone therapy causes hot flushes, loss of libido, loss of muscle and bone, and low mood. This trial asked whether men could take breaks from it. After ten years the answer was uncomfortable: the breaks felt better for three months, and the trial could not rule out a worse chance of survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-hussain-swog-9346-intermittent-androgen-deprivation-nejm-2013/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/nejmoa1212299>, <https://pubmed.ncbi.nlm.nih.gov/23550669/>, <https://clinicaltrials.gov/study/NCT00002651> ;
  onco:tag "prostate-evidence" ;
  schema:sameAs <https://doi.org/10.1056/nejmoa1212299> ;
  schema:datePublished "2013"^^xsd:gYear ;
  schema:author "Hussain M, Tangen CM, Berry DL, et al." ;
  onco:related <https://onco.cc/key-papers/paper-langley-lancet/>, <https://onco.cc/key-papers/paper-denmeade-transformer-bipolar-androgen-therapy-jco-2021/>, <https://onco.cc/roadmaps/prostate-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mhspc/> ;
  onco:sections <https://onco.cc/fronts/hormonal/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:drugs <https://onco.cc/drugs/leuprolide/>, <https://onco.cc/drugs/bicalutamide/> ;
  onco:terms <https://onco.cc/terms/adt/>, <https://onco.cc/terms/psa/>, <https://onco.cc/terms/quality-of-life/>, <https://onco.cc/terms/hazard-ratio/>, <https://onco.cc/terms/intermittent-androgen-deprivation/>, <https://onco.cc/terms/other-cause-mortality/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-survivorship/> ;
  onco:journals <https://onco.cc/journals/nejm/> .