# OnCo record paper-indigo-nejm-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-indigo-nejm-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-indigo-nejm-2023" ;
  schema:name "INDIGO: vorasidenib, the first targeted drug for IDH-mutant low-grade glioma"@en ;
  schema:description "An oral drug that blocks the mutant IDH enzyme more than doubled the time before slow-growing IDH-mutant brain tumours progressed, letting patients postpone radiotherapy and chemotherapy for years."@en ;
  schema:url <https://onco.cc/key-papers/paper-indigo-nejm-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2304194>, <https://clinicaltrials.gov/study/NCT04164901> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2304194> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Mellinghoff IK, van den Bent MJ, Blumenthal DT, et al." ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/mri/> ;
  onco:targets <https://onco.cc/targets/idh/> ;
  onco:drugs <https://onco.cc/drugs/vorasidenib/> ;
  onco:companies <https://onco.cc/companies/servier/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/oncogene-addiction/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-trial-design/> ;
  onco:journals <https://onco.cc/journals/nejm/> .