# OnCo record paper-jones-pancreatic-core-pathways-science-2008 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-jones-pancreatic-core-pathways-science-2008/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-jones-pancreatic-core-pathways-science-2008" ;
  schema:name "Core signaling pathways in human pancreatic cancers revealed by global genomic analyses"@en ;
  schema:description "The first complete reading of the protein-coding genes in 24 pancreatic cancers found an average of 63 changes per tumour that, however varied gene by gene, hit the same dozen cellular pathways in almost every case."@en ;
  schema:url <https://onco.cc/key-papers/paper-jones-pancreatic-core-pathways-science-2008/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.1164368>, <https://pubmed.ncbi.nlm.nih.gov/18772397/> ;
  schema:sameAs <https://doi.org/10.1126/science.1164368> ;
  schema:datePublished "2008"^^xsd:gYear ;
  schema:author "Jones S, Zhang X, Parsons DW, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/cdkn2a/>, <https://onco.cc/targets/smad4/> ;
  onco:institutions <https://onco.cc/institutions/johns-hopkins/> ;
  onco:pathways <https://onco.cc/pathways/pancreatic-cancer-signalling/> ;
  onco:terms <https://onco.cc/terms/driver-mutation/> ;
  onco:people <https://onco.cc/people/bert-vogelstein/>, <https://onco.cc/people/kenneth-kinzler/>, <https://onco.cc/people/nickolas-papadopoulos/>, <https://onco.cc/people/elizabeth-jaffee/>, <https://onco.cc/people/anirban-maitra/> ;
  onco:journals <https://onco.cc/journals/science/> .