# OnCo record paper-katherine-nejm-2019 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-katherine-nejm-2019/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-katherine-nejm-2019" ;
  schema:name "KATHERINE: switching to T-DM1 when HER2-positive breast cancer survives pre-surgery treatment"@en ;
  schema:description "Women whose HER2-positive breast cancer was still present at surgery after chemotherapy and trastuzumab had half the risk of relapse if their post-surgery treatment was switched to the antibody-drug conjugate T-DM1 instead of continuing trastuzumab."@en ;
  schema:url <https://onco.cc/key-papers/paper-katherine-nejm-2019/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1814017>, <https://clinicaltrials.gov/study/NCT01772472> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa1814017> ;
  schema:datePublished "2019"^^xsd:gYear ;
  schema:author "von Minckwitz G, Huang CS, Mano MS, et al." ;
  onco:related <https://onco.cc/ideas/idea-post-neoadjuvant-adc/> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab-emtansine/>, <https://onco.cc/drugs/trastuzumab/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/pcr/>, <https://onco.cc/terms/rcb/>, <https://onco.cc/terms/neoadjuvant-adjuvant/> ;
  onco:trials <https://onco.cc/trials/destiny-breast03/>, <https://onco.cc/trials/destiny-breast11/> ;
  onco:people <https://onco.cc/people/gunter-von-minckwitz/>, <https://onco.cc/people/sibylle-loibl/>, <https://onco.cc/people/shao-zhi-ming/>, <https://onco.cc/people/charles-geyer/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dormancy-mrd/>, <https://onco.cc/bottlenecks/b-trial-design/> ;
  onco:journals <https://onco.cc/journals/nejm/> .
